Enteropathy-associated T-cell Lymphoma (EATL) with intracranial metastasis : a rare and dismal condition
| Journal | Volume 83 - 2020 |
| Issue | Fasc.1 - Case reports |
| Author(s) | Y. Y. Chuah 1 2, T. Tashi 3, Y. Y. Lee 4, T. Y. Fu 5, C. A. Shih 6 7 8 |
| Full article |
 PAGES 77-80 VIEW FREE PDF |
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Affiliations: (1) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Ping Tung Christian Hospital, Ping Tung, Taiwan
(2) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan (3) Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA (4) Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia (5) Department of Pathology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan (6) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Antai Medical Care Corporation, Antai Tian-Sheng Memorial Hospital, Pingtung County, Taiwan (7) National Yang-Ming University, Taipei City, Taiwan (8) Department of Nursing, Meiho University, Ping Tung, Taiwan |
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Background: Enteropathy-associated T-cell lymphoma (EATL) is a rare type of gastrointestinal non-Hodgkin’s Lymphoma. EATL with intracranial metastasis is even rarer. We report a case of EATL with intracranial metastasis. Case Presentation: A 36-years old man presented with five weeks history of intractable diarrhea. Colonoscopy was normal, but abdominal computed tomography (CT) scan revealed mural thickening at duodenojejunal junction, and subsequent jejunofiberoscopy showed a circumferential ulceration at the jejunum. Histo-immunopathology confirmed the diagnosis of enteropathyassociated T-cell lymphoma (EATL) type II. His disease course proved to be aggressive and refractory to standard front-line chemotherapy, and eventually progressed through second-line salvage regimen with CNS and intracranial involvement. He died nine months after the initial diagnosis. Conclusion: EATL with brain metastasis is a very rare occurrence with dismal prognosis. Keywords: enteropathy-associated T-cell Lymphoma, intracranial metastasis. |
| The authors declare that they have no conflict of interest. |
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© Acta Gastro-Enterologica Belgica. PMID 32233276 |
